Primary Causes & Action Plans
Total IgE
Elevated in atopic dermatitis; indicates allergic/immune dysregulation IgE elevation indicates Th2 immune skewing characteristic of atopic dermatitis. High IgE often indicates atopy (allergies, asthma, eczema).
Target < 150 IU/mL
Suggested Action Plan
Rebalance immune response through probiotics, vitamin D optimization, anti-inflammatory diet. Eliminate food triggers identified via testing.
hs-CRP
Systemic inflammation driving skin inflammation Elevated hs-CRP indicates systemic inflammation driving skin flares. Anti-inflammatory intervention reduces skin symptoms.
Target < 1.0 mg/L
Suggested Action Plan
Anti-inflammatory diet, omega-3 supplementation, exercise reduce hs-CRP and skin inflammation. Retest in 3 months.
Vitamin D
Critical for immune tolerance and skin barrier integrity Vitamin D deficiency is associated with increased eczema severity and is immunosuppressive. Vitamin D optimization reduces flares.
Target > 50 ng/mL
Suggested Action Plan
Supplement vitamin D3 4000-5000 IU daily. Target 60-80 ng/mL. Most people with atopic dermatitis benefit from high-dose vitamin D.
Microbiome Dysbiosis
Dysbiosis associated with impaired skin barrier and increased allergen permeability Dysbiotic microbiome increases intestinal permeability, allowing allergen translocation and systemic immune activation. Dysbiosis is correctable.
Target Healthy diversity
Suggested Action Plan
Restore dysbiosis through probiotics and prebiotic fiber. Improve skin by healing gut barrier.